| Person's Name | Language | Explanation |
| Saffie | English | Pet form of SAFFRON |
| Saffron | English | From the English word which refers either to a spice, the crocus flower from which it is harvested, or the yellow-orange colour of the spice. It ultimately derives from Arabic za´faran. |
| Sage | English | From the English word, which denotes either a type of spice or else a wise person. |
| Sakura | Japanese | Means "cherry blossom" in Japanese. |
| Sanna | Scandinavian | Scandinavian short form of SUSANNA. It can also be derived from Swedish sann meaning "true". |
| Savannah | English | Means simply "savannah" from the English word for the large grassy plain, ultimately deriving from the Taino (Native American) word zabana. |
| Sayuri | Japanese | Means "small lily" in Japanese. |
| Sethunya | African | Means "bloom, flower" in Tswana. |
| Shoshana | Jewish | Original Hebrew form of SUSANNA |
| Sirvart | Armenian | Means "love rose" in Armenian. |
| Su | English | Short form of SUSANNA |
| Sue | English | Short form of SUSANNA |
| Sukie | English | Pet form of SUSANNA |
| Susan | English | Short form of SUSANNA. A notable bearer was Susan B. Anthony, an American feminist of the 19th century. |
| Susanita | Spanish | Spanish pet form of SUSANNA |
| Susanna | English, Italian, Biblical | From Sousanna, the Greek form of the Hebrew name Shoshannah which was derived from the Hebrew word shushan meaning "lily" (in modern Hebrew this also means "rose"). In the New Testament this is the name of a woman who ministered to Christ. It also occurs in the Old Testament Apocrypha as the name of a woman falsely accused of adultery. The prophet Daniel clears her name by tricking her accusers, who end up being condemned themselves. |
| Susannah | English, Biblical (Variant) | Form of SUSANNA found in some versions of the Old Testament. |
| Susanne | German | German form of SUSANNA |
| Suse | German | German short form of SUSANNA |
| Susie | English | Pet form of SUSANNA |
| Suzanna | English | Variant of SUSANNA |
| Suzanne | French | French form of SUSANNA |
| Suzette | French | French pet form of SUSANNA |
| Suzie | English | Pet form of SUSANNA |
| Suzy | English | Pet form of SUSANNA |
| Sources: Compilation from Behind the Name website. |